Results 571-580 of about 1,000
Date: 2024-01-01 Authors: Gatica-Arias A, Pereira LF. Journal: Methods in molecular biology (Clifton, N.J.) - Live-Cell Sender-Receiver Co-cultures for Quantitative Measurement of Paracrine Signaling Dynamics, Gene Expression, and... new windowParacrine signaling is a fundamental process regulating tissue development, repair, and pathogenesis of diseases such as cancer. Herein we describe a method for quantitatively measuring paracrine signaling dynamics, and resultant gene expression
Date: (2023) Authors: Michael Pargett , Abhineet R. Ram , Vaibhav Murthy , Alexander E. Davies Ref: Computational Modeling of Signaling Networks Date: 2024-01-01 Authors: Villalta-Villalobos J, Pereira LF, Gatica-Arias A. Journal: Methods in molecular biology (Clifton, N.J.) - Caenorhabditis elegans, a 1 mm long free-living nematode, is a traditional model animal for genetic investigations of various biological processes. Characteristic features that make C. elegans a powerful model of choice for eukaryotic genetic studies
Date: (2023) Authors: Takuma Sugi Ref: Genome Editing in Animals - Analyses of Genetic Regulation of the Nervous System in the Nematode Caenorhabditis elegans. new window
Date: 2024-01-01 Authors: Huang TT, Mori I. Journal: Methods in molecular biology (Clifton, N.J.) - Epigenome editing is a powerful approach for the establishment of a chromatin environment with desired properties at a selected genomic locus, which is used to influence the transcription of target genes and to study properties and functions of gene
Date: (2023) Authors: Pavel Bashtrykov , Nivethika Rajaram , Albert Jeltsch Ref: Epigenomics - Mutations in mitochondrial DNA (mtDNA) are responsible for several severe diseases that have no available cures. The multicopy nature of the mitochondrial genome means that mutations often exist in a state known as heteroplasmy, where both mutant and
Date: (2023) Authors: Wendy K. Shoop , Sandra R. Bacman , Jose Domingo Barrera-Paez , Carlos T. Moraes Date: 2024-01-01 Authors: Liao X, Li L. Journal: Methods in molecular biology (Clifton, N.J.) - Ribonucleoprotein (RNP)-Mediated Allele Replacement in Barley (Hordeum vulgare L.) Leaves new windowVarietal differences within a species with agronomic importance are often based on minor changes in the genomic sequence. For example, fungus-resistant and fungus-susceptible wheat varieties may vary in only one amino acid. The situation is similar
Date: (2023) Authors: Martin Becker , Goetz Hensel Ref: Plant Genome Engineering - High-Throughput Base Editing-Mediated Artificial Evolution Streamlines Trait Gene Identification in Rice new windowBase Editing-Mediated Gene Evolution (BEMGE) method develops novel rice germplasms with mutations in any endogenous gene through employing both Cas9n-based cytosine and adenine base editors combined with an sgRNA library tiling the full-length coding
Date: (2023) Authors: Fang Yan , Man Yu , Meixia Wang , Huanbin Zhou Ref: Base Editors