Results 11-20 of about 359
- Spatialtranscriptomics (ST) has advanced our understanding of tissue regionalization by enabling the visualization of gene expression within whole-tissue sections, but current approaches remain plagued by the challenge of achieving single-ce
Date: (2025) Authors: Jiyuan Yang , Ziqian Zheng , Yun Jiao , Kaiwen Yu ... Jiyang Yu - Protocol for interpretable and context-specific single-cell-informed deconvolution of bulk RNA-seq data. new window
Date: 2025-03-04 Authors: Malpetti D, Mangili F, Bolis M, Rinaldi A, Legouis D, Ruinelli L, Cippà P, Azzimonti L. Journal: STAR protocols - Spatially resolved transcriptomics technologies provide high-throughput measurements of gene expression in a tissue slice, but the sparsity of these data complicates analysis of spatial gene expression patterns. We address this issue by deriving a
Date: (2025) Authors: Uthsav Chitra , Brian J. Arnold , Hirak Sarkar , Kohei Sanno ... Benjamin J. Raphael - Protocol for the dissection, immunostaining, and imaging of whole-mount mouse choroid plexus. new window
Date: 2025-02-27 Authors: Byer LIJ, Xu H, Lehtinen MK. Journal: STAR protocols - Transcriptomics is an extremely important area of molecular biology and is a powerful tool for studying all RNA molecules in an organism. Conventional transcriptomic technologies include microarrays and RNA sequencing, and the rapid development of
Date: (2025) Authors: Qingcong Zheng , Rongjie Lin , Chunfu Zheng Ref: Antiviral Innate Immunity - Protocol to recover single-cell gene expression profiles from spatial transcriptomics data using cluster computing. new window
Date: 2025-02-12 Authors: Lee YJ, Chen H, Lugo-Martinez J. Journal: STAR protocols - Spatially resolved genome-wide joint profiling of epigenome and transcriptome with spatial-ATAC-RNA-seq and spatial-CUT&... new windowThe epigenome of a cell is tightly correlated with gene transcription, which controls cell identity and diverse biological activities. Recent advances in spatial technologies have improved our understanding of tissue heterogeneity by analyzing
Date: (2025) Authors: Haikuo Li , Shuozhen Bao , Negin Farzad , Xiaoyu Qin ... Rong Fan - Protocol to boost the robustness and accuracy of spatial transcriptomics algorithms using ensemble techniques. new window
Date: 2025-01-28 Authors: Cai J, Wu S, Cheng H, Zhong W, Yuan GC, Ma P. Journal: STAR protocols - Spatial molecular profiling has provided biomedical researchers valuable opportunities to better understand the relationship between cellular localization and tissue function. Effectively modeling multimodal spatial omics data is crucial for
Date: (2025) Authors: Kyle Coleman , Amelia Schroeder , Melanie Loth , Daiwei Zhang ... Mingyao Li - Protocol for the isolation of silk glands from silkworms for snRNA-seq and spatial transcriptomics. new window
Date: 2025-01-12 Authors: Ma Y, Dong K, Hu J, Tang Y, Xu H. Journal: STAR protocols