Results 21-30 of about 359
- Traditional tissue profiling approaches have evolved from bulk studies to single-cell analysis over the last decade; however, the spatial context in tissues and microenvironments has always been lost. Over the last 5 years, spatial technologies have
Date: (2025) Authors: Arutha Kulasinghe , Naomi Berrell , Meg L. Donovan , Benedikt S. Nilges Ref: Gene Expression Analysis - Inferring multi-slice spatially resolved gene expression from H&E-stained histology images with STMCL. new window
Date: 2025-01-02 Authors: Shi Z, Zhu F, Min W. Journal: Methods (San Diego, Calif.) - The rise of cellular immunotherapy for cancer treatment has led to the utilization of immune oncology cocultures to simulate T cell interactions with cancer cells for assessing their antitumor response. Previously, we developed BEHAV3D, a
Date: (2025) Authors: A. K. Wezenaar , U. Pandey , F. Keramati , M. Hernandez-Roca ... A. C. Rios - Integrating Tissue Microarray to GeoMx<sup>®</sup> Digital Spatial Profiler : Spatial Transcriptomics Assay ... new window
Date: 2025-01-01 Authors: Dechamma D, Moorthy M, Bhat V, Ramaswamy G. Journal: Methods in molecular biology (Clifton, N.J.) - Spatial transcriptomic tools are an upcoming and powerful way to investigate targeted gene expression patterns within tissues. These tools offer the unique advantage of visualizing and understanding gene expression while preserving tissue integrity,
Date: (2025) Authors: Ashish Shelar , Anasuya Dighe Ref: HOX Genes Date: 2025-01-01 Authors: Kulasinghe A, Berrell N, Donovan ML, Nilges BS. Journal: Methods in molecular biology (Clifton, N.J.) - The brain, like many organs in the body, comprises an array of different cell types that act in concert to achieve its many functions. These cell types vary dramatically in molecular composition, morphology, spatial distribution, electrical activity,
Date: (2025) Authors: Vilas Menon Ref: Gene Expression Analysis Date: 2025-01-01 Authors: Gentile E, Maynard A, He Z, Treutlein B. Journal: Methods in molecular biology (Clifton, N.J.) - The phenotypic and functional states of cells are modulated by a complex interactive molecular hierarchy of multiple omics layers, involving the genome, epigenome, transcriptome, proteome and metabolome. Spatial omics approaches have enabled the
Date: (2025) Authors: Pengfei Guo , Liran Mao , Yufan Chen , Chin Nien Lee ... Yanxiang Deng - Optimizing Xenium In Situ data utility by quality assessment and best-practice analysis workflows new windowThe Xenium In Situ platform is a new spatialtranscriptomics product commercialized by 10x Genomics, capable of mapping hundreds of genes in situ at subcellular resolution. Given the multitude of commercially available spatialtranscripto
Date: (2025) Authors: Sergio Marco Salas , Louis B. Kuemmerle , Christoffer Mattsson-Langseth , Sebastian Tismeyer ... Mats Nilsson