Results 131-140 of about 900
- Multi-omics Resources for Understanding Gene Regulation in Response to ER Stress in Plants. new window
Date: 2024-01-01 Authors: Ko DK, Brandizzi F. Journal: Methods in molecular biology (Clifton, N.J.) - In recent years, it has been shown that Z-DNA formation in DNA plays functionally significant roles in nucleic acid metabolism, such as gene expression, chromosome recombination, and epigenetic regulation. The reason for the identification of these
Date: (2023) Authors: Atsushi Inose-Maruyama , Shuya Kasai , Ken Itoh Ref: Z-DNA - Discovery of off-target CRISPR–Cas activity in patient-derived cells and animal models is crucial for genome editing applications, but currently exhibits low sensitivity. We demonstrate that inhibition of DNA-dependent protein kinase catalytic
Date: (2023) Authors: Roger S. Zou , Yang Liu , Oscar E. Gaido , Maximilian F. Konig ... Taekjip Ha - Single-Nucleus ATAC-seq for Mapping Chromatin Accessibility in Individual Cells of Murine Hearts. new window
Date: 2024-01-01 Authors: Yekelchyk M, Li X, Guenther S, Braun T. Journal: Methods in molecular biology (Clifton, N.J.) - The equilibrium between stem cell self-renewal and differentiation followed by proper lineage specification of progenitor cells is considered imperative for maintaining intestinal homeostasis. In the hierarchical model, intestinal differentiation is
Date: (2023) Authors: Shahadat Rahman , Xi Lan , Christopher Terranova , Rayan El-Kholdi ... Chia-Wei Cheng Ref: Intestinal Differentiated Cells - Understanding functional effects of genetic variants is one of the key challenges in human genetics, as much of disease-associated variation is located in non-coding regions with typically unknown putative gene regulatory effects. One of the most
Date: (2023) Authors: François Aguet , Kaur Alasoo , Yang I. Li , Alexis Battle ... Tuuli Lappalainen - Cleavage Under Targets & Release Using Nuclease (CUT&RUN) of Histone Modifications in Epidermal Stem Cells of Adult Muri... new window
Date: 2024-01-01 Authors: Flora P, Ezhkova E. Journal: Methods in molecular biology (Clifton, N.J.) - Heat shock proteins (HSP) are rapidly induced after proteotoxic stresses such as heat shock and accumulate at high concentrations in cells. HSP induction involves primarily a family of heat shock transcription factors (HSF) that bind the heat shock
Date: (2023) Authors: Heyoun Bunch , Stuart K. Calderwood Ref: Chaperones - Computational Analysis Tutorial for Chimeric Small Noncoding RNA: Target RNA Sequencing Libraries. new window
Date: 2023-12-01 Authors: Eadara S, Li X, Eiss EA, Meffert MK. Journal: Journal of visualized experiments : JoVE - Recent development of targeted manipulation of histone modification enables us to experimentally and directly test the functional relevance of histone modifications accumulated at specific genomic regions. In particular, dCas9 epigenome editing has
Date: (2023) Authors: Hiroto S. Fukushima , Hiroyuki Takeda , Ryohei Nakamura Ref: Epigenomics