Results 311-320 of about 900
Date: 2022-01-01 Authors: Schächner C, Merkl PE, Pilsl M, Schwank K, Hergert K, Kruse S, Milkereit P, Tschochner H, Griesenbeck J. Journal: Methods in molecular biology (Clifton, N.J.) - Generation and Analysis of dsDNA Breaks for Checkpoint and Repair Studies in Fission Yeast new windowDamage to DNA elicits both checkpoint and repair responses. These are complex events that involve many genes whose products assemble at lesions and form signaling cascades to recruit additional factors and regulate the cell cycle. The fission yeast
Date: (2021) Authors: Rohana Ramalingam , Matthew J. O’Connell Ref: Cell Cycle Checkpoints - Circadian gene transcription transmits timing information and drives cyclic physiological processes across various tissues. Recent studies indicate that oscillating enhancer activity is a major driving force of rhythmic gene transcription. Functional
Date: (2021) Authors: Bin Fang , Dongyin Guan , Mitchell A. Lazar Ref: Circadian Clocks Date: 2022-01-01 Authors: Larkin A, Ames A, Seman M, Ragunathan K. Journal: Methods in molecular biology (Clifton, N.J.) - Effective gene expression prediction from sequence by integrating long-range interactions new windowHow noncoding DNA determines gene expression in different cell types is a major unsolved problem, and critical downstream applications in human genetics depend on improved solutions. Here, we report substantially improved gene expression prediction
Date: (2021) Authors: Žiga Avsec , Vikram Agarwal , Daniel Visentin , Joseph R. Ledsam ... David R. Kelley Date: 2022-01-01 Authors: Servant N. Journal: Methods in molecular biology (Clifton, N.J.) - Analyses of Promoter , Enhancer, and Nucleosome Organization in Mammalian Cells by MNase-Seq new windowMNase-Seq is a genome-wide procedure that allows mapping of DNA associated to nucleosomes following micrococcal nuclease digestion. It is a rapid and robust technology useful for the analysis of chromatin properties genome-wide at the resolution of
Date: (2021) Authors: Cyril Esnault , Talha Magat , Encar García-Oliver , Jean-Christophe Andrau Ref: Enhancers and Promoters - Genome-Wide Analysis of RNA–Protein Interactions in Plasmodium falciparum Using eCLIP-Seq new windowOver the last decades, identification of RNA–proteins complexes and their binding sites was challenging. Recently, techniques based on crosslinking, immunoprecipitation, and high-throughput sequencing have been developed. An optimized method, called
Date: (2021) Authors: Thomas Hollin , Steven Abel , Karine G. Le Roch Ref: Parasite Genomics - The comparison of methylomes from immune cells enables the identification of differentially methylated regions and thereby region-associated gene loci. Those regions can be used to discriminate one immune cell population from the other, as well as
Date: (2021) Authors: Stefan Floess , Jochen Huehn Ref: T-Helper Cells - Analysis of Epigenetic Modifications During Vegetative and Reproductive Development in Cereals Using ChromatinImmunoprec... new windowThe study of heritable genetic changes that do not implicate alterations in the DNA sequence—epigenetics—represents one of the most prolific and expanding fields in plant biology during the last two decades. With a focus on DNA methylation and
Date: (2020) Authors: Kevin Begcy , Thomas Dresselhaus Ref: Cereal Genomics