Results 351-360 of about 900
- Understanding the rate and patterns of genome variation is becoming ever more amenable to whole-genome analysis through advances in DNA sequencing, which may, at least in some circumstances, have supplanted more localized analyses by cellular and
Date: (2020) Authors: Emma M. Briggs , Catarina A. Marques , Joao Reis-Cunha , Jennifer Black ... Richard McCulloch Ref: Trypanosomatids Date: 2022-01-01 Authors: Kitchen P, Gaston K, Jayaraman PS. Journal: Methods in molecular biology (Clifton, N.J.) - Expanded CAG/CTG repeats are genetically unstable and, upon expression, cause neurological and neuromuscular diseases. The molecular mechanisms of repeat instability and expression remain poorly understood despite their importance for the
Date: (2020) Authors: Cinzia Cinesi , Bin Yang , Vincent Dion Ref: Trinucleotide Repeats - Pluripotent cells in the inner cell mass (ICM) or epiblast of mammalian embryos exhibit the capacity to differentiate into all cells represented in the three germ layers. Embryonic stem (ES) cells can be derived from the ICM of preimplantation stage
Date: (2020) Authors: Benjamin L. Kidder Ref: Stem Cell Transcriptional Networks Date: 2022-01-01 Authors: Cinkornpumin JK, Hossain I, Pastor WA. Journal: Methods in molecular biology (Clifton, N.J.) - Integration of Multi-omics Data for Expression Quantitative Trait Loci (eQTL) Analysis and eQTL Epistasis new windowExpression quantitative trait loci (eQTL) mapping studies identify genetic loci that regulate gene expression. eQTL mapping studies can capture gene regulatory interactions and provide insight into the genetic mechanism of biological systems.
Date: (2020) Authors: Mingon Kang , Jean Gao Ref: eQTL Analysis - Method for Investigation of Photobiological Effects of Light on Human Skin Cells Mediated by Low Doses of Light new windowDriven by evolution, human skin cells have developed an extraordinary ability both to sense and to respond to the photons of sunlight through a plethora of photobiological interactions, activating intracellular signalling cascades and regulating skin
Date: (2020) Authors: Charles Mignon , Natallia E. Uzunbajakava Ref: Molecular Dermatology - Targeted downregulation of select endogenous plant genes is known to confer disease or pest resistance in crops and is routinely accomplished via transgenic modification of plants for constitutive gene silencing. An attractive alternative to the use
Date: (2020) Authors: Huan Zhang , Honglu Zhang , Gozde S. Demirer , Eduardo González-Grandío ... Markita P. Landry - We recently introduced Cleavage Under Targets & Tagmentation (CUT&Tag), an epigenomic profiling strategy in which antibodies are bound to chromatin proteins in situ in permeabilized nuclei. These antibodies are then used to tether the cut-a
Date: (2020) Authors: Hatice S. Kaya-Okur , Derek H. Janssens , Jorja G. Henikoff , Kami Ahmad , Steven Henikoff Date: 2022-01-01 Authors: Dori M, Forcato M. Journal: Methods in molecular biology (Clifton, N.J.)