Results 291-300 of about 900
- The successful assembly of nucleosomes following DNA replication is critically important for both the inheritance of epigenetic information and the maintenance of genome integrity. This process, termed DNA replication-coupled (RC) nucleosome
Date: (2021) Authors: Zhiyun Xu , Jianxun Feng , Qing Li Ref: Yeast Protocols Date: 2022-03-04 Authors: Singh RS, Arna AB, Dong H, Yadav M, Aggarwal A, Wu Y. Journal: Methods (San Diego, Calif.) - Genome-Wide Analysis of c-MYC-Regulated mRNAs and miRNAs and c-MYC DNA-Binding by Next-Generation Sequencing new windowThe c-MYC oncogene is activated in ~50% of all tumors and its product, the c-MYC transcription factor, regulates numerous processes, which contribute to tumor initiation and progression. Therefore, the genome-wide characterization of c-MYC targets
Date: (2021) Authors: Rene Jackstadt , Markus Kaller , Antje Menssen , Heiko Hermeking Ref: The Myc Gene Date: 2022-02-26 Authors: Debnath S, Lu X, Lal A, Sharma S. Journal: Methods (San Diego, Calif.) - Genome architecture and function are strictly related to nuclear structures, which contact chromatin at specific regions, regulating its compaction and three-dimensional higher-order structure, therefore contributing to specialized gene expression
Date: (2021) Authors: Federica Lucini , Andrea Bianchi , Chiara Lanzuolo Ref: Capturing Chromosome Conformation Date: 2022-02-12 Authors: Yang Y, Li Y, Li XB, Li TX, Qi J, Zhou X, Li P. Journal: Computational and mathematical methods in medicine - Investigating the chromatin landscape of the early mammalian embryo is essential to understand how epigenetic mechanisms may direct reprogramming and cell fate allocation. Genome-wide analyses of the epigenome in preimplantation mouse embryos have
Date: (2021) Authors: Mrinmoy Pal , Jop Kind , Maria-Elena Torres-Padilla Ref: Epigenetic Reprogramming During Mouse Embryogenesis - Single-Cell Factor Localization on Chromatin using Ultra-Low Input Cleavage Under Targets and Release using Nuclease. new window
Date: 2022-02-01 Authors: Lardo SM, Hainer SJ. Journal: Journal of visualized experiments : JoVE - CRISPR-Cas9 technologies have dramatically increased the ease of targeting DNA sequences in the genomes of living systems. The fusion of chromatin-modifying domains to nuclease-deactivated Cas9 (dCas9) has enabled targeted epigenome editing in both
Date: (2021) Authors: Matthew P. Gemberling , Keith Siklenka , Erica Rodriguez , Katherine R. Tonn-Eisinger ... Charles A. Gersbach - Induction of cancer cell stemness in glioma through glycolysis and the long noncoding RNA HULC-activated FOXM1/AGR2/HIF-... new window
Date: 2022-01-10 Authors: Li YP, Liu Y, Xiao LM, Chen LK, Tao EX, Zeng EM, Xu CH. Journal: Laboratory investigation; a journal of technical methods and pathology