Results 161-170 of about 900
- Analysis of Transgenerational Epigenetic Inheritance in C. elegans Using a Fluorescent Reporter and Chromatin Immunoprec... new window
Date: 2023-05-05 Authors: Li C, Bhagoutie PAW, Lao V, Saltzman AL. Journal: Journal of visualized experiments : JoVE - Proper mitochondrial DNA (mtDNA) levels are critical for many cellular biological functions and are associated with aging and many mitochondria disorders. Defects in core subunits of the mtDNA replication machinery lead to decreased mtDNA levels.
Date: (2023) Authors: Xie Xie , Xuefeng Zhu Ref: Mitochondrial DNA Date: 2023-03-17 Authors: Dix MF, Liu P, Cui G, Della Valle F, Orlando V, Aranda M. Journal: Journal of visualized experiments : JoVE - Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease characterized by hepatosteatosis, liver cell injury, and inflammation. The pathogenesis of NASH involves dysregulated transcription of genes involved in
Date: (2022) Authors: Simiao Xu , Yangyang Liu , Ji Miao Ref: Non-Alcoholic Steatohepatitis - Adipocyte-Specific ATAC-Seq with Adipose Tissues Using Fluorescence-Activated Nucleus Sorting. new window
Date: 2023-03-17 Authors: Kim K, Taleb S, So J, Wann J, Cheol Roh H. Journal: Journal of visualized experiments : JoVE - Studies of DNA–protein interactions have revealed regulatory mechanisms of DNA replication, repair, remodeling, and transcription. Perturbation of any or all of these processes result in differential gene expression that can lead to tumor
Date: (2022) Authors: Tara Dobson , Jyothishmathi Swaminathan Ref: Medulloblastoma Date: 2023-02-24 Authors: Ocañas SR, Isola JVV, Saccon TD, Pham KD, Chucair-Elliott AJ, Schneider A, Freeman WM, Stout MB. Journal: Journal of visualized experiments : JoVE - Monitoring Chromatin Regulation in Planarians Using ChromatinImmunoprecipitation Followed by Sequencing (ChIP-seq ) new windowPlanarians are an accessible model system to study animal regeneration and stem cells. Over the last two decades, new molecular techniques have provided us with powerful tools to understand whole-body regeneration and pluripotent adult stem cells
Date: (2022) Authors: Divya Sridhar , Aziz Aboobaker Ref: Whole-Body Regeneration - Optimized lentiviral vector transduction of adherent cells and analysis in sulforhodamine B proliferation and chromatin ... new window
Date: 2023-02-09 Authors: Li L, Trent JC, Eid JE. Journal: STAR protocols - ChromatinImmunoprecipitation Sequencing (ChIP-seq) Protocol for Small Amounts of Frozen Biobanked Cardiac Tissue new windowChromatinimmunoprecipitation and sequencing (ChIP-seq) is a well-established method to study the epigenetic profile at the genome-wide scale, including histone modifications and DNA–protein interactions. It provides valuable insights to bett
Date: (2022) Authors: Jiayi Pei , Noortje A. van den Dungen , Folkert W. Asselbergs , Michal Mokry , Magdalena Harakalova Ref: Chromatin