Results 551-560 of about 900
- Comprehensive mapping of protein–DNA interactions is essential to uncover the mechanisms involved in gene regulation. However, the data generated has been sparse given the number of regulatory elements and transcription factors (TFs) encoded in the
Date: (2018) Authors: Jared A. Sewell , Juan I. Fuxman Bass Ref: Two-Hybrid Systems Date: 2020-07-06 Authors: Li Y. Journal: Methods (San Diego, Calif.) - Integrated Microarray-based Tools for Detection of Genomic DNA Damage and Repair Mechanisms new windowThe genetic information contained within the DNA molecule is highly susceptible to chemical and physical insult, caused by both endogenous and exogenous sources that can generate in the order of thousands of lesions a day in each of our cells
Date: (2018) Authors: Patrick Eijk , Yumin Teng , Mark R. Bennet , Katie E. Evans ... Simon H. Reed Ref: Genome Instability - An Optimized Chromatin Immunoprecipitation Protocol for Quantification of Protein-DNA Interactions. new window
Date: 2020-06-19 Authors: de Jonge WJ, Brok M, Kemmeren P, Holstege FCP. Journal: STAR protocols - This methods article described a protocol aiming at mapping E. coli Topoisomerase IV (Topo IV) binding and cleavage activity sites on the genome. The approach is readily applicable to any Type II topoisomerase on a broad variety of gram-positive and
Date: (2018) Authors: Hafez Sayyed , Olivier Espéli Ref: DNA Topoisomerases Date: 2020-06-01 Authors: Smith JP, Sheffield NC. Journal: Current protocols in human genetics - Nuclear receptors play an important role in prostate cancer and the androgen receptor is a key transcription factor in regulation of cellular events. Androgen receptor-associated coregulators may be upregulated or downregulated in prostate cancer.
Date: (2018) Authors: Simon Schlanger , Hannelore V. Heemers Ref: Prostate Cancer - A new methodological approach for in vitro determination of the role of DNA methylation on transcription factor binding ... new window
Date: 2020-05-13 Authors: Sabatucci A, Berchet V, Bellia F, Maccarrone M, Dainese E, D'Addario C, Pucci M. Journal: Journal of neuroscience methods - Computational Methods for Analysis of the DNA-Binding Preferences of Cys2His2 Zinc-Finger Proteins new windowCys2His2 zinc-finger proteins (C2H2-ZFPs) constitute the largest class of human transcription factors (TFs) and also the least characterized one. Determining the DNA sequence preferences of C2H2-ZFPs is an important first step toward elucidating
Date: (2018) Authors: Berat Doğan , Hamed S. Najafabadi Ref: Zinc Finger Proteins Date: 2020-05-01 Authors: Gilchrist MJ, Cho KWY, Veenstra GJC. Journal: Cold Spring Harbor protocols